Trial intelligence / Profile preview

TROPION-Lung15: Dato-DXd with or without osimertinib versus platinum chemotherapy in EGFR-mutant advanced non-small cell lung cancer after progression on osimertinib

CTR20244119Phase 3Active

Sponsor
AstraZeneca
Start
Feb 2025
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

A Phase 3 trial of datopotamab deruxtecan, osimertinib, pemetrexed, cisplatin, carboplatin in non-small cell lung cancer (NSCLC), sponsored by AstraZeneca. Started Feb 2025; status: active.

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Drugs

datopotamab deruxtecanosimertinibpemetrexedcisplatincarboplatin
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Conditions

non-small cell lung cancer (NSCLC)

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