Trial intelligence / Profile preview

B-United: daplusiran/tomligisiran followed by bepirovirsen in chronic hepatitis B on nucleos(t)ide analogue background therapy

CTR20244953Phase 2Active

Sponsor
GSK
Start
Feb 2025
Modality
Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of tomligisiran and bepirovirsen in Chronic Hepatitis B (CHB) (4 arms), sponsored by GSK. Started Feb 2025; status: active.

02

Drugs

tomligisiranbepirovirsen
03

Conditions

Chronic Hepatitis B (CHB)

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