Trial intelligence / Profile preview

eVOLVE-HNSCC: volrustomig versus observation after definitive concurrent chemoradiotherapy in unresectable locally advanced head and neck squamous cell carcinoma

CTR20244969Phase 3Active

Sponsor
AstraZeneca
Start
May 2025
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, open-label trial in head and neck squamous cell carcinoma (HNSCC) comparing Volrustomig sequential therapy with Observation (2 arms). Primary endpoint: Progression-free survival. Started May 2025; status: active.

02

Drugs

volrustomig
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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