Trial intelligence / Profile preview

AcTFirst phase 3 study of 225Ac-PSMA-617 + ARPI versus standard treatment in PSMA-positive metastatic castration-resistant prostate cancer

CTR20252315Phase 3Active

Sponsor
Novartis
Start
Jul 2025
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Alpha Emitters → Radiopharmaceuticals, Small Molecules
Countries
1
01

Overview

A Phase 3 trial of actinium-225 PSMA-617 in metastatic castration-resistant prostate cancer (mCRPC), sponsored by Novartis. Started Jul 2025; status: active.

02

Drugs

actinium-225 PSMA-617
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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