Trial intelligence / Profile preview

SHASTA-10 open-label extension of plozasiran in adults with severe hypertriglyceridemia

CTR20252375Phase 3Active

Sponsor
Arrowhead Pharmaceuticals
Start
Dec 2025
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

A Phase 3 trial of plozasiran in hypertriglyceridemia, sponsored by Arrowhead Pharmaceuticals. Started Dec 2025; status: active.

02

Drugs

plozasiran
03

Conditions

hypertriglyceridemia

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