Trial intelligence / Profile preview

Phase Ib/II study of TYK-00540 plus enzalutamide in metastatic castration-resistant prostate cancer after failure of one prior novel endocrine therapy

CTR20252940Phase 2Active

Sponsor
TYK Medicines
Start
Jul 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of TYK-00540 and enzalutamide in prostate cancer (PCa) (2 arms), sponsored by TYK Medicines. Primary endpoints: Safety and dose-limiting toxicity in dose escalation and Radiographic progression-free survival in dose expansion. Started Jul 2025; status: active.

02

Drugs

TYK-00540enzalutamide
03

Conditions

prostate cancer (PCa)

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