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Phase I/II study of glofitamab alone or with R-ICE after obinutuzumab pretreatment in pediatric and young adult relapsed/refractory mature B-cell non-Hodgkin lymphoma

CTR20252960Phase 2Active

Sponsor
Roche
Start
Jul 2025
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

A Phase 2 trial of glofitamab in mature B-cell lymphoma, Burkitt lymphoma (BL), B cell acute lymphoblastic leukemia (B-ALL), diffuse large B-cell lymphoma (DLBCL), primary mediastinal large B-cell lymphoma (PMBCL), sponsored by Roche. Started Jul 2025; status: active.

02

Drugs

glofitamab
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Conditions

mature B-cell lymphomaBurkitt lymphoma (BL)B cell acute lymphoblastic leukemia (B-ALL)diffuse large B-cell lymphoma (DLBCL)primary mediastinal large B-cell lymphoma (PMBCL)

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