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Phase 3 double-blind randomized study of zolbetuximab + pembrolizumab + chemotherapy as first-line treatment for HER2-negative, CLDN18.2-positive, PD-L1-positive advanced gastric or gastroesophageal junction adenocarcinoma

CTR20253090Phase 3Active

Sponsor
Astellas Pharma
Start
Nov 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

A Phase 3 trial of zolbetuximab in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma, sponsored by Astellas Pharma. Started Nov 2025; status: active.

02

Drugs

zolbetuximab
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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Available in the Gosset platform where reported.

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