Trial intelligence / Profile preview

Datopotamab deruxtecan versus docetaxel in previously treated TROP2-positive advanced or metastatic non-squamous NSCLC without actionable driver alterations

CTR20254226Phase 3Active

Sponsor
AstraZeneca
Start
Dec 2025
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

A Phase 3 trial of datopotamab deruxtecan, docetaxel in non-small cell lung cancer (NSCLC), sponsored by AstraZeneca. Started Dec 2025; status: active.

02

Drugs

datopotamab deruxtecandocetaxel
03

Conditions

non-small cell lung cancer (NSCLC)

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