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Pumitamig plus chemotherapy versus nivolumab plus chemotherapy in previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma

CTR20260794Phase 3Active

Sponsor
Bristol Myers Squibb
Start
Mar 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial of pumitamig in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma and esophageal adenocarcinoma (EAC) (2 arms), sponsored by Bristol Myers Squibb. Primary endpoints: Objective response rate, Progression-free survival and 1 more. Started Mar 2026; status: active.

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Drugs

pumitamig
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)

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