Trial intelligence / Profile preview

IBI310 plus sintilimab-based first-line study in unresectable or metastatic hepatocellular carcinoma

CTR20261005Phase 3Active

Sponsor
Innovent Biologics
Start
Apr 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of IBI310, sintilimab, bevacizumab, oxaliplatin and capecitabine in hepatocellular carcinoma (HCC) (2 arms), sponsored by Innovent Biologics. Primary endpoints: Objective response rate, Progression-free survival and 2 more. Started Apr 2026; status: active.

02

Drugs

IBI310sintilimabbevacizumaboxaliplatincapecitabine
03

Conditions

hepatocellular carcinoma (HCC)

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