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Carboxyamidotriazole soft capsules plus osimertinib versus osimertinib as first-line treatment for EGFR-mutant advanced non-small cell lung cancer with bone metastases

CTR20261504Phase 2Active

Sponsor
Yinzhu Pharmaceutical
Start
Apr 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Carboxyamidotriazole + osimertinib with Osimertinib control (2 arms). Primary endpoints: Dose-limiting toxicity and Progression-free survival. Started Apr 2026; status: active.

02

Drugs

carboxyamidotriazoleosimertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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