Trial intelligence / Profile preview

Phase I/II study of BMS-986458 monotherapy and combination therapy in relapsed/refractory non-Hodgkin lymphoma

CTR20261571Phase 2Active

Sponsor
Bristol Myers Squibb
Start
Jan 2024
Modality
PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of bms-986458 in non-Hodgkin lymphoma (NHL), diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL), sponsored by Bristol Myers Squibb. Primary endpoints: Incidence of adverse events and Incidence of treatment-related safety syndromes. Started Jan 2024; status: active.

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Drugs

bms-986458
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Conditions

non-Hodgkin lymphoma (NHL)diffuse large B-cell lymphoma (DLBCL)follicular lymphoma (FL)

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