Trial intelligence / Profile preview

ASP3082 plus mFOLFIRINOX or NALIRIFOX for first-line KRAS G12D-mutant metastatic pancreatic adenocarcinoma

CTR20262630Phase 3Active

Sponsor
Astellas Pharma
Start
Apr 2026
Modality
PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
1
01

Overview

A Phase 3 trial of setidegrasib in pancreatic adenocarcinoma (PDAC), sponsored by Astellas Pharma. Started Apr 2026; status: active.

02

Drugs

setidegrasib
03

Conditions

pancreatic adenocarcinoma (PDAC)

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