Trial intelligence / Profile preview

Phase II study of VVD-133214 plus pembrolizumab versus pembrolizumab alone in first-line MSI-H/dMMR advanced colorectal cancer

CTR20262977Phase 2Active

Sponsor
Bayer
Start
Jul 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in colorectal cancer (CRC) comparing VVD-133214 + pembrolizumab with Pembrolizumab monotherapy (2 arms). Primary endpoint: 6-month landmark progression-free survival rate. Started Jul 2026; status: active.

02

Drugs

VVD-133214pembrolizumab
03

Conditions

colorectal cancer (CRC)

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