Trial intelligence / Profile preview

Phase 3 randomized open-label study of setidegrasib versus docetaxel in previously treated KRAS G12D-mutant advanced non-small cell lung cancer

CTR20262991Phase 3Active

Sponsor
Astellas Pharma
Start
Aug 2026
Modality
PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
1
01

Overview

A Phase 3 trial of setidegrasib in non-small cell lung cancer (NSCLC), sponsored by Astellas Pharma. Started Aug 2026; status: active.

02

Drugs

setidegrasib
03

Conditions

non-small cell lung cancer (NSCLC)

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