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HF-POLARIS: NNC0487-0111 vs placebo in obese patients with heart failure with preserved or mildly reduced ejection fraction

CTR20263200Phase 3Active

Sponsor
Novo Nordisk
Start
May 2026
Modality
Small Molecules, Peptides
Countries
1
01

Overview

A Phase 3 trial of amycretin in heart failure (HF), heart failure with preserved ejection fraction (HFpEF), heart failure with reduced ejection fraction (HFrEF), obesity, type 2 diabetes mellitus (T2DM), sponsored by Novo Nordisk. Started May 2026; status: active.

02

Drugs

amycretin
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Conditions

heart failure (HF)heart failure with preserved ejection fraction (HFpEF)heart failure with reduced ejection fraction (HFrEF)obesitytype 2 diabetes mellitus (T2DM)

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