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Symbiotic-GYN-18: PF-08634404 plus chemotherapy versus pembrolizumab plus chemotherapy in pMMR advanced or recurrent endometrial cancer
CTR20263941Phase 3Active
- Sponsor
- Pfizer
- Start
- Oct 2026
- Modality
- Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial in endometrial cancer (EC) comparing PF-08634404 plus chemotherapy with Pembrolizumab plus chemotherapy (2 arms). Primary endpoint: Progression-free survival by blinded independent central review. Started Oct 2026; status: active.
02
Drugs
PF-08634404pembrolizumab
03
Conditions
endometrial cancer (EC)
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