Trial intelligence / Profile preview

HARMONi-GU1: ivonescimab + enfortumab vedotin versus pembrolizumab + enfortumab vedotin in first-line advanced urothelial carcinoma

CTR20263988Phase 3Active

Sponsor
CTTQ-Akeso
Start
Oct 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

A Phase 3 trial of ivonescimab, enfortumab vedotin, pembrolizumab in transitional cell carcinoma (TCC), sponsored by CTTQ-Akeso. Started Oct 2026; status: active.

02

Drugs

ivonescimabenfortumab vedotinpembrolizumab
03

Conditions

transitional cell carcinoma (TCC)

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