Trial intelligence / Profile preview

Letrozole-based endometrial preparation for frozen blastocyst transfer in women with PCOS

IRCT20080831001141N38Phase 3Completed

Sponsor
Royan Institute
Start
Sep 2021
Modality
Recombinant Proteins and Enzymes, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of letrozole, human chorionic gonadotropin, gonadotropin-releasing hormone agonist, estradiol valerate and progesterone in polycystic ovary syndrome (PCOS) and infertility (2 arms), sponsored by Royan Institute. Primary endpoint: Clinical pregnancy rate. Started Sep 2021; status: completed.

02

Drugs

letrozolehuman chorionic gonadotropingonadotropin-releasing hormone agonistestradiol valerateprogesterone
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Conditions

polycystic ovary syndrome (PCOS)infertility

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