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Oral methotrexate for recurrent chronic rhinosinusitis with nasal polyps
IRCT20120404009375N2Phase 3Completed
- Sponsor
- Ahvaz Jundishapur University of Medical Sciences
- Start
- Mar 2026
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, double-blind trial in chronic rhinosinusitis with nasal polyps (CRSwNP) comparing Oral methotrexate with Placebo (2 arms). Primary endpoint: Nasal endoscopy score. Started Mar 2026; status: completed.
02
Drugs
methotrexate
03
Conditions
chronic rhinosinusitis with nasal polyps (CRSwNP)
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