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Transforaminal epidural steroid plus hyaluronic acid versus steroid plus hyaluronidase for lumbar radiculopathy

IRCT20130523013442N39Phase 3Completed

Sponsor
Shahid Beheshti University of Medical Sciences
Start
Apr 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Therapeutic Enzymes → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, double-blind trial in Herniated Lumbar Disk, lumbar spinal stenosis (LSS) and lumbosacral radiculopathy comparing Methylprednisolone + hyaluronic acid with Methylprednisolone + hyaluronidase (2 arms). Primary endpoints: Pain assessment and Functional improvement. Started Apr 2026; status: completed.

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Drugs

methylprednisolonehyaluronic acidhyaluronidase
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Conditions

Herniated Lumbar Disklumbar spinal stenosis (LSS)lumbosacral radiculopathy

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