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Melatonin vs dexmedetomidine to reduce propofol dose in BIS-guided anesthesia for femur fracture surgery

IRCT20141009019470N103Phase 3Completed

Sponsor
Shiraz University of Medical Sciences
Start
Feb 2021
Modality
Small Molecules
Countries
1
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Overview

Phase 3, randomised trial in femoral fracture comparing Melatonin + propofol arm with Dexmedetomidine + propofol arm (2 arms). Primary endpoints: Propofol dose requirements during induction of anesthesia and Propofol dose requirements during maintenance of anesthesia. Started Feb 2021; status: completed.

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Drugs

melatonindexmedetomidinepropofol
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Conditions

femoral fracture

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