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Deferasirox + deferiprone versus deferoxamine + deferiprone for iron overload in transfusion-dependent beta-thalassemia

IRCT20190106042262N1Phase 3Completed

Sponsor
Isfahan University of Medical Sciences
Start
Feb 2018
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in beta thalassemia and transfusional hemosiderosis comparing Deferasirox + deferiprone with Deferoxamine + deferiprone (2 arms). Primary endpoints: Heart MRI T2*, Liver MRI T2* and 3 more. Started Feb 2018; status: completed.

02

Drugs

deferasiroxdeferipronedeferoxamine
03

Conditions

beta thalassemiatransfusional hemosiderosis

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