Trial intelligence / Profile preview

Low-dose ondansetron plus dexamethasone for prevention of postoperative nausea and vomiting after total knee arthroplasty

IRCT20190325043107N87Phase 3Recruiting

Sponsor
Tabriz University of Medical Sciences
Start
Oct 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in postoperative nausea and vomiting (PONV) comparing Ondansetron + dexamethasone with Dexamethasone + placebo (2 arms). Primary endpoint: Postoperative nausea and vomiting. Started Oct 2026; status: recruiting.

02

Drugs

ondansetrondexamethasone
03

Conditions

postoperative nausea and vomiting (PONV)

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