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Urinary alkalinization with sodium bicarbonate to enhance intravesical BCG efficacy in non-muscle-invasive bladder cancer
IRCT20200402046915N5Phase 3Recruiting
- Sponsor
- Shahid Beheshti University of Medical Sciences
- Start
- Oct 2026
- Modality
- Small Molecules, Vaccines & Immunotherapeutics
- Countries
- 1
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Overview
Phase 3, randomised, double-blind trial in bladder cancer and non-muscle-invasive bladder cancer (NMIBC) comparing BCG plus sodium bicarbonate with BCG plus placebo (2 arms). Primary endpoints: Tumor recurrence rate and Disease progression rate. Started Oct 2026; status: recruiting.
02
Drugs
sodium bicarbonatebcg vaccine
03
Conditions
bladder cancernon-muscle-invasive bladder cancer (NMIBC)
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