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Tranexamic acid versus vitamin K prophylaxis for perioperative bleeding in femoral surgery
IRCT20211011052726N6Phase 3Completed
- Sponsor
- Mazandaran University of Medical Sciences
- Start
- Dec 2025
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial in intraoperative bleeding comparing TXA group with Vitamin K group (2 arms). Primary endpoints: Total estimated blood loss, Hemoglobin drop and 2 more. Started Dec 2025; status: completed.
02
Drugs
tranexamic acidphytomenadione
03
Conditions
intraoperative bleeding
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