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Atropine vs ipratropium bromide vs amitriptyline for clozapine-induced sialorrhea
IRCT20211110053031N1Phase 2Completed
- Sponsor
- Shiraz University of Medical Sciences
- Start
- Jul 2022
- Modality
- Classical Binding Small Molecules → Small Molecules, Small Molecules
- Countries
- 1
01
Overview
Phase 2, randomised, single-blind trial in hypersalivation comparing Atropine arm, Ipratropium bromide arm and Amitriptyline arm (3 arms). Primary endpoint: Reduction of clozapine-induced sialorrhea. Started Jul 2022; status: completed.
02
Drugs
atropineipratropium bromideamitriptyline
03
Conditions
hypersalivation
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