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Tapering fentanyl/midazolam vs switching to dexmedetomidine for restlessness during ventilator weaning in PICU

IRCT20211221053474N1Phase 3Completed

Sponsor
Tabriz University of Medical Sciences
Start
Mar 2023
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3 trial of fentanyl, midazolam and dexmedetomidine in sedative use disorder (SUD), agitation and Weaning failure (2 arms), sponsored by Tabriz University of Medical Sciences. Primary endpoint: Restlessness during ventilator weaning. Started Mar 2023; status: completed.

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Drugs

fentanylmidazolamdexmedetomidine
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Conditions

sedative use disorder (SUD)agitationWeaning failure

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