Trial intelligence / Profile preview

Rituximab plus haplo-identical allogeneic activated NK cells for relapsed or refractory B-cell non-Hodgkin lymphoma

IRCT20230801058996N6Phase 2Completed

Sponsor
Shahid Beheshti University of Medical Sciences
Start
Jun 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
Countries
1
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Overview

Phase 2, open-label trial of rituximab and allogeneic natural killer cells in B-cell non-Hodgkin lymphoma (B-NHL) (2 arms), sponsored by Shahid Beheshti University of Medical Sciences. Primary endpoint: Adverse effects during or after combination therapy with allogeneic NK cells and rituximab. Started Jun 2024; status: completed.

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Drugs

rituximaballogeneic natural killer cells
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Conditions

B-cell non-Hodgkin lymphoma (B-NHL)

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