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Methadone versus methadone plus olanzapine in heroin and methamphetamine dependence with novelty-seeking temperament
IRCT20230914059433N1Phase 3Completed
- Sponsor
- Arak University of Medical Sciences
- Start
- Apr 2023
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial in opioid use disorder (OUD) and amphetamine dependence comparing Methadone maintenance therapy + olanzapine with Methadone maintenance therapy (2 arms). Primary endpoints: Relapse and Boredom. Started Apr 2023; status: completed.
02
Drugs
methadoneolanzapine
03
Conditions
opioid use disorder (OUD)amphetamine dependence
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