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Oral clonidine versus intravenous tranexamic acid for blood loss reduction during posterior lumbar spine fusion
IRCT20231113060037N4Phase 3Recruiting
- Sponsor
- Shahid Beheshti University of Medical Sciences
- Start
- Oct 2026
- Modality
- Small Molecules
- Countries
- 1
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Overview
Phase 3, randomised, double-blind trial in spinal stenosis and spondylolisthesis comparing Oral clonidine arm, Intravenous tranexamic acid arm and Placebo arm (3 arms). Primary endpoints: Intraoperative blood loss and Total volume of packed red blood cell transfusion. Started Oct 2026; status: recruiting.
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Drugs
clonidinetranexamic acid
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Conditions
spinal stenosisspondylolisthesis
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