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Riluzole plus methylprednisolone versus methylprednisolone plus placebo for acute thoracolumbar spinal cord injury

IRCT20240722062515N1Phase 3Completed

Sponsor
Alborz University of Medical Sciences
Start
Sep 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in spinal cord injury (SCI) and thoracolumbar fracture comparing Riluzole + methylprednisolone with Placebo + methylprednisolone (2 arms). Primary endpoints: Functional recovery, Frankel scale and 11 more. Started Sep 2024; status: completed.

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Drugs

riluzolemethylprednisolone
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Conditions

spinal cord injury (SCI)thoracolumbar fracture

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