Trial intelligence / Profile preview

Letrozole pretreatment plus misoprostol versus misoprostol alone for missed abortion

IRCT20250414065324N1Phase 3Completed

Sponsor
Hormozgan University of Medical Sciences
Start
Jul 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in missed abortion comparing Letrozole pretreatment followed by misoprostol with Placebo pretreatment followed by misoprostol (2 arms). Primary endpoints: Complete uterine evacuation rate and Need for surgical curettage. Started Jul 2025; status: completed.

02

Drugs

letrozolemisoprostol
03

Conditions

missed abortion

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