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Intracoronary nitroprusside versus adenosine for FFR measurement in moderate coronary stenosis

IRCT20251005067509N1Phase 3Completed

Sponsor
Tehran University of Medical Sciences
Start
Nov 2025
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, open-label, single-arm trial of sodium nitroprusside and adenosine in coronary arteriosclerosis, sponsored by Tehran University of Medical Sciences. Primary endpoints: Fractional flow reserve after adenosine and nitroprusside and Non-inferiority of nitroprusside-induced maximal hyperemia versus adenosine. Started Nov 2025; status: completed.

02

Drugs

sodium nitroprussideadenosine
03

Conditions

coronary arteriosclerosis

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