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Metformin adjunctive therapy for opioid use disorder on methadone maintenance
IRCT20260215068879N1Phase 2Recruiting
- Sponsor
- Institute for Cognitive Science Studies
- Start
- Aug 2026
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 2, randomised, double-blind trial in opioid use disorder (OUD) comparing Metformin + methadone with Placebo + methadone (2 arms). Primary endpoints: Change in total Subjective Opiate Withdrawal Scale score and Change in attentional bias index by dot probe task. Started Aug 2026; status: recruiting.
02
Drugs
metformin
03
Conditions
opioid use disorder (OUD)
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