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Intravenous acetaminophen versus oral ibuprofen for PDA closure in preterm infants

IRCT20260607069688N1Phase 3Recruiting

Sponsor
Qom University of Medical Sciences
Start
Jun 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in patent ductus arteriosus (PDA) comparing Intravenous acetaminophen with Oral ibuprofen (2 arms). Primary endpoints: Rate of PDA closure confirmed by echocardiography, Need for additional medical treatment and 5 more. Started Jun 2026; status: recruiting.

02

Drugs

acetaminophenibuprofen
03

Conditions

patent ductus arteriosus (PDA)

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