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Cardiac function in neonates with neonatal abstinence syndrome treated with morphine + phenobarbital versus morphine + clonidine
IRCT20260829070824N1Phase 3Completed
- Sponsor
- Kerman University of Medical Sciences
- Start
- Nov 2024
- Modality
- Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, triple-blind trial of morphine, phenobarbital and clonidine in neonatal abstinence syndrome (NAS) (2 arms), sponsored by Kerman University of Medical Sciences. Primary endpoints: Left ventricular ejection fraction, Mitral inflow E/A ratio and 2 more. Started Nov 2024; status: completed.
02
Drugs
morphinephenobarbitalclonidine
03
Conditions
neonatal abstinence syndrome (NAS)
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