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Vonoprazan versus pantoprazole for stress ulcer prophylaxis in ICU patients
IRCT20260908070967N1Phase 3Not yet recruiting
- Sponsor
- Kermanshah University of Medical Sciences
- Start
- Nov 2026
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial in Acute Stress Gastritis and gastrointestinal bleeding comparing Pantoprazole with Vonoprazan (2 arms). Primary endpoints: Occurrence of clinically important gastrointestinal bleeding during intensive care unit stay, Occurrence of overt gastrointestinal bleeding without hemodynamic compromise and 4 more. Planned start Nov 2026; status: not yet recruiting.
02
Drugs
vonoprazanpantoprazole
03
Conditions
Acute Stress Gastritisgastrointestinal bleeding
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