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Autologous stem cell transplantation for AL amyloidosis

ISRCTN01207094Phase 2Completed

Sponsor
HOVON
Start
Sep 2000
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
01

Overview

Phase 2, open-label, single-arm trial of vincristine, doxorubicin, dexamethasone, filgrastim and melphalan in light-chain amyloidosis, sponsored by HOVON. Primary endpoints: Response and Overall survival. Started Sep 2000; status: completed.

02

Drugs

vincristinedoxorubicindexamethasonefilgrastimmelphalan
03

Conditions

light-chain amyloidosis

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