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TORPEDO-CF trial of optimal Pseudomonas eradication therapy in cystic fibrosis
ISRCTN02734162Phase 4Completed
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
- Start
- May 2010
- Modality
- Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01
Overview
Phase 4, randomised, open-label trial in cystic fibrosis (CF) and Pseudomonal infection comparing IV ceftazidime + IV tobramycin + nebulized colistin with Oral ciprofloxacin + nebulized colistin (2 arms). Primary endpoint: Sustained successful eradication of Pseudomonas aeruginosa. Started May 2010; status: completed.
02
Drugs
ceftazidimetobramycinciprofloxacincolistin
03
Conditions
cystic fibrosis (CF)Pseudomonal infection
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