Trial intelligence / Profile preview

Vorinostat + bortezomib + dexamethasone for relapsed or refractory multiple myeloma

ISRCTN08577602Phase 2Completed

Sponsor
University of Leeds
Start
Mar 2012
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
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Overview

Phase 2, open-label, single-arm trial of vorinostat, bortezomib and dexamethasone in multiple myeloma (MM), sponsored by University of Leeds. Primary endpoint: Proportion achieving at least partial response within 8 cycles. Started Mar 2012; status: completed.

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Drugs

vorinostatbortezomibdexamethasone
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Conditions

multiple myeloma (MM)

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