Trial intelligence / Profile preview

Emicizumab study of health, physical activity, and joint outcomes in moderate or severe hemophilia A without FVIII inhibitors

ISRCTN10101701Phase 4Active, not recruiting

Sponsor
Roche
Start
Jan 2022
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
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Overview

Phase 4, open-label trial of emicizumab in hemophilia A (3 cohorts), sponsored by Roche. Primary endpoints: Joint status over time by HEAD-US with focus on synovitis, Clinical joint status by HJHS v2.1 and 9 more. Started Jan 2022; status: active, not recruiting.

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Drugs

emicizumab
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Conditions

hemophilia A

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