Trial intelligence / Profile preview

Rucaparib with nivolumab and/or ipilimumab versus rucaparib alone in relapsed high-grade serous ovarian cancer

ISRCTN10490346Phase 2Completed

Sponsor
NHS Greater Glasgow and Clyde
Start
May 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 2, randomised, open-label trial in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) comparing Rucaparib alone, Rucaparib + nivolumab and Rucaparib + nivolumab + ipilimumab (3 arms). Primary endpoint: Progression-free survival. Started May 2019; status: completed.

02

Drugs

rucaparibnivolumabipilimumab
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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