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NET-02 second-line therapy trial in progressive poorly differentiated extrapulmonary neuroendocrine carcinoma

ISRCTN10996604Phase 2Completed

Sponsor
The Christie
Start
Oct 2018
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

Phase 2, randomised, open-label trial in extrapulmonary neuroendocrine carcinoma (EPNEC) comparing nal-IRI + fluorouracil + folinic acid with docetaxel (2 arms). Primary endpoint: Progression-free survival rate at 6 months. Started Oct 2018; status: completed.

02

Drugs

nanoliposomal irinotecanfluorouracilfolinic aciddocetaxel
03

Conditions

extrapulmonary neuroendocrine carcinoma (EPNEC)

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