Trial intelligence / Profile preview

Phase 2 study of subcutaneous amivantamab regimens in EGFR-mutated advanced or metastatic non-small cell lung cancer

ISRCTN11527992Phase 2Completed

Sponsor
Janssen Pharmaceutical
Start
Oct 2022
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
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Overview

Phase 2, open-label trial of amivantamab in non-small cell lung cancer (NSCLC) and Nonhematologic neoplasms (6 cohorts), sponsored by Janssen Pharmaceutical. Primary endpoints: Objective response rate by investigator assessment, Number of participants with adverse events and 3 more. Started Oct 2022; status: completed.

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Drugs

amivantamab
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Conditions

non-small cell lung cancer (NSCLC)Nonhematologic neoplasms

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