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ICS-containing triple therapy versus non-ICS dual bronchodilator therapy for cardiovascular vascular aging markers in COPD

ISRCTN11747857Phase 4Terminated

Sponsor
Imperial College London
Start
Feb 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
01

Overview

Phase 4, randomised, open-label trial in chronic obstructive pulmonary disease (COPD) comparing Trixeo Aerosphere arm with Bevespi Aerosphere arm (2 arms). Primary endpoint: Degree of senescence in endothelial progenitors. Started Feb 2025; status: terminated.

02

Drugs

budesonideBEVESPI AEROSPHERE
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Conditions

chronic obstructive pulmonary disease (COPD)

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