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LOCI trial: letrozole versus clomifene for ovulation induction in women with polycystic ovarian syndrome
ISRCTN11828358Phase 3Completed
- Sponsor
- University of Birmingham
- Start
- Mar 2020
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
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Overview
Phase 3, randomised, double-blind trial of letrozole, clomiphene and metformin in polycystic ovary syndrome (PCOS) (4 arms), sponsored by University of Birmingham. Primary endpoint: Live birth at and beyond 34 completed weeks of gestation. Started Mar 2020; status: completed.
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Drugs
letrozoleclomiphenemetformin
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Conditions
polycystic ovary syndrome (PCOS)
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