Trial intelligence / Profile preview

UMIT-2 Trial for treatments of Crimean-Congo haemorrhagic fever

ISRCTN12205320Phase 2Recruiting

Sponsor
Liverpool School of Tropical Medicine
Start
Jun 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
01

Overview

Phase 2, randomised, open-label trial in Crimean–Congo hemorrhagic fever (CCHF) comparing Optimised Standard of Care, Favipiravir and Ribavirin (3 arms). Primary endpoint: Proportion of patients with undetectable CCHF viral RNA in blood by day 7. Started Jun 2026; status: recruiting.

02

Drugs

favipiravirribavirin
03

Conditions

Crimean–Congo hemorrhagic fever (CCHF)

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