Trial intelligence / Profile preview

Phase 3 trial of ARO-APOC3 in adults with familial chylomicronemia syndrome

ISRCTN12904794Phase 3Completed

Sponsor
Arrowhead Pharmaceuticals
Start
Oct 2021
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Phase 3, randomised trial of plozasiran in primary chylomicronemia (FCS) (4 arms), sponsored by Arrowhead Pharmaceuticals. Primary endpoint: Percent change from baseline in fasting triglycerides at Month 10. Started Oct 2021; status: completed.

02

Drugs

plozasiran
03

Conditions

primary chylomicronemia (FCS)

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